Propanc Biopharma nears production of synthetic pancreatic proenzymes

Propanc Biopharma Inc (OTCMKTS:PPCB) revealed Monday that it is on the cusp of producing synthetic versions of the two pancreatic proenzymes – trypsinogen and chymostrypsinogen – which make up its lead product, the cancer-fighting drug PRP.

“We are pleased with the recent advancements made through our research program, as we are able to produce synthetic recombinant versions of the two proenzymes, trypsinogen and chymostrypsinogen,” said Dr. Julian Kenyon, Propancs chief scientific officer. “The two active ingredients are currently naturally derived from animal sources, which combine to form our lead product candidate, PRP.”

The “significant advances” made by Propancs POP1 research program – which is being conducted with scientists at the Universities of Jaén and Granada in Spain – bring the Australian company closer to producing large quantities of trypsinogen and chymostrypsinogen for commercial use.

READ: Propanc Biopharma wins US patent to better protect its lead cancer-fighting drug PRP

“As we seek to expand our product pipeline, our vision is to create a new drug product class that provides a solution for the treatment and prevention of recurring and spreading malignant tumors, once perceived as untreatable,” added James Nathanielsz, Propancs CEO.

A key goal of the POP1 project – now being carried out in research labs at Jaén and Granada – is to synthesize this critical pair of pancreatic proenzymes to produce crystalized proteins that can be kept for lengthy periods without refrigeration. Figuring out a way to do this is crucial to the extension of PRPs shelf life as well as its distribution internationally, especially in warmer areas and developing countries.

PRP works by suppressing cellular pathways involved in the Read More – Source

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