CCTV caught the ill-fated moment a student got into a car she thought was an Uber.
Samantha Josephson, 21, was found dead hours later and the alleged driver was arrested for kidnap and murder.
Her blood and her mobile phone were found in the car, along with wet wipes and bleach, police said.
The child safety locks were also enabled, making it harder for her to escape.
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Smanthas body was found by turkey hunters dumped in a rural area in South Carolina.
Nathaniel David Rowland, 24, was arrested shortly afterwards when police saw him driving the car Samantha was last seen getting into.
He is said to have tried to flee on foot before police apprehended him.
Her actual Uber driver cancelled the ride when she failed to show up at around 2am on Friday in Columbia, South Carolina after a night out with friends.
Police said Samantha had got into a dark-coloured car which appears to have been a Chevrolet Impala.
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